IJARSAI INTERNATIONAL JOURNAL OF ADVANCED RESEARCH SCIENTIFIC ANALYSIS & INFERENCES
Article Title: Theoretical Investigation of Inhibitory Action of Flavanoids against Nipha Virus through Molecular Docking
Author(s): Joseph Libin K.L., Assistant Professor “Department of Chemistry, St. Michael's College, Cherthala , Email: jigjoselibin@gmail.com,
Jibin K. Varughese, Jr HSST Chemistry, KMHSS Kuttoor North, Malappuram, Email: jibinkchem@gmail.com
Discipline: Chemistry
Received: 22 Aug 2024| Revised Submission: 25 Sep 2024 | Accepted: 14 Dec 2024| Available Online: 15 Mar 2025
DOI:
Abstract: Nipah virus is a bat-borne, zoonotic virus that causes Nipah virus infection in humans and other animals, a disease with a very high mortality rate (40-75%). Numerous disease outbreaks caused by Nipah virus have occurred in South east Africa and South east Asia. Nipah virus belongs to the genus Henipavirus along with the Hendra virus, which has also caused disease outbreaks . Nipah virus (NiV) is an RNA virus belonging to family Paramyxoviridae. It belongs to the genus Henipavirus which also contains Hendra virus (HeV) and the recently described Cedar virus. Bats are the natural reservoir of Henipaviruses. It first emerged in Malaysia in 1998 and has since caused several outbreaks in South and Southeast Asia.
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